The primary objective of the BIOMEDE-IA project (2020-2024) was to predict by machine learning methods the main genomic mutations of patients with diffuse intrinsic pontine gliomas from their clinical and imaging (multi-parametric MRI) features, to manage the cases for which biopsy is not available. We also predicted subjects with long survival; i.e. greater than two years. This project, carried out in collaboration with Gustave-Roussy, Necker Hospital and Neurospin, is based on data acquired by clinical trials BIOMEDE (2014-2019) and BIOMEDE2 (2022-2028).
Publications :DOI :10.1093/neuonc/noae064.360, DOI:10.3389/fmed.2023.1071447, DOI:10.3390/cancers13236113,DOI: 10.1109/EMBC46164.2021.9629704, DOI :10.1007/978-3-030-80209-7_83
People involved in the lab: Joseph Al Khoury, Frédérique Frouin (PI). Alumni: Fahad Khalid, Stéphanie Jehan-Besson.