Publications 2024

  1. Lekadir K, Frangi AF, Porras AR, Glocker B, Cintas C, Langlotz CP, Weicken E, Asselbergs FW, Prior F, Collins GS, Kaissis G, Tsakou G, Buvat I, Kalpathy-Cramer J, Mongan J, Schnabel JA, Kushibar K, Riklund K, Marias K, Amugongo LM, Fromont LA, Maier-Hein L, Alberich LC, Martí-Bonmatí L, Cardoso MJ, Bobowicz M, Shabani M, Tsiknakis M, Zuluaga MA, Fritzsche MC, Camacho M, Linguraru MG, Wenzel M, De Bruijne M, Tolsgaard MG, Goisauf M, Abadía MC, Papanikolaou N, Lazrak N, Pujol O, Osuala R, Napel S, Joshi S, Klein S, Aussó S, Rogers WA, Puig-Bosch X, Salahuddin Z, Starmans MPA, and the FUTURE-AI Consortium. FUTURE-AI: International consensus guideline for trustworthy and deployable artificial intelligence in healthcare. BMJ British Medical Journal, in press, 2024.

  2. Captier N, Lerousseau M, Orlhac F, Hovhannisyan-Baghdasarian N, Luporsi M, Woff E, Lagha S, Salamoun Feghali P, Lonjou C, Beaulaton C, Salmon H, Walter T, Buvat I, Girard N, Barillot E. Integration of clinical, pathological, radiological, and transcriptomic data improves the prediction of first-line immunotherapy outcome in metastatic non-small cell lung cancer. Nature Comm, in press, 2024.

  3. Bonfrate A, Ronga MG, Patriarca A, Heinrich S, De Marzi L. Monte Carlo modeling of a commercial machine and experimental setup for Flash-Minibeam irradiations with electrons. Med Phys, 1-11, 2024. DOI: https://doi.org/10.1002/mp.17492

  4. Granado-González M, Price T, Gonella L, Moustakas K, Hirono T, Hemperek T, De Marzi L, Patriarca A. First test beam of the DMAPS-based proton tracker at the pMBRT facility at the Curie Institute. Phys Med Biol. 69(21), 2024. DOI: 10.1088/1361-6560/ad84b3.

  5. Potiron S, Iturri L, Juchaux M, Espenon J, Gilbert C, McGarrigle J, Ortiz Catalan R, Fernandez-Rodriguez A, Sebrié C, Jourdain L, De Marzi L, Créhange G, Prezado Y. The significance of dose heterogeneity on the anti-tumor response of minibeam radiation therapy. Radiother Oncol. 201:110577, 2024. DOI: 10.1016/j.radonc.2024.110577.

  6. Renard S, Parent L, De Marzi L, Tsoutsou P, Kirova Y. Electron radiation therapy: Back to the future? Cancer Radiother. 28(6-7):553-559, 2024. DOI: 10.1016/j.canrad.2024.07.013.

  7. Gesualdi F, de Marzi L, Dutreix M, Favaudon V, Fouillade C, Heinrich S. A multidisciplinary view of flash irradiation. Cancer Radiother. 28(5):453-462, 2024. DOI: 10.1016/j.canrad.2024.07.003.

  8. Sitarz M, Ronga MG, Gesualdi F, Bonfrate A, Wahl N, De Marzi L. Implementation and validation of a very-high-energy electron model in the matRad treatment planning system. Med Phys, in press, 2024. DOI: 10.1002/mp.17392.

  9. Loap P, Vu-Bezin J, De Marzi L, Kirova Y. Proton therapy reduces the effective dose to immune cells in breast cancer patients. Strahlenther Onkol. in press, DOI: 10.1007/s00066-024-02263-1.

  10. González-Vegas R, Yousef I, Seksek O, Ortiz R, Bertho A, Juchaux M, Nauraye C, Marzi L, Patriarca A, Prezado Y, Martínez-Rovira I. Investigating the biochemical response of proton minibeam radiation therapy by means of synchrotron-based infrared microspectroscopy. Sci Rep. 14(1):11973, 2024. DOI: 10.1038/s41598-024-62373-9.

  11. Legdeur N, Badissi M, Venkatraghavan V, Woodworth DC, Orlhac F, Vidal JS, Barkhof F, Kawas CH, Visser PJ, Corrada MM, Muller M, Rhodius-Meester HFM. The temporal relation of physical function with cognition and the influence of brain health in the oldest-old: The UCI 90+ Study and EMIF-AD 90+ Study. Gerontology, in press, 2024.

  12. Seban RD, Champion L, De Moura A, Lerebours F, Loirat D, Pierga JY, Djerroudi L, Genevee T, Huchet V, Jehanno N, Bidard FC, Buvat I. Pre-treatment [18F]FDG PET/CT biomarkers for the prediction of antibody-drug conjugates efficacy in metastatic breast cancer, Eur J Nucl Med Mol Imaging, in press, 2024.

  13. Buvat I, Weber WA. Is ChatGPT a reliable ghostwriter? J Nucl Med, 65(10):1499-1502, 2024. DOI: 10.2967/jnumed.124.268341.

  14. Paty LP, Degueldre S, Provost C, Schmitt C, Trump L, Fouque J, Vriamont C, Valla F, Gendron T, Madar O. Development of a versatile [68Ga]Ga-FAPI-46 automated synthesis suitable to multi-elutions of germanium-68/gallium-68 generators. Front Chem, 12:1411312. Front Chem, 2024. DOI: 10.3389/fchem.2024.1411312. 

  15. Loap P, De Marzi L, Decroocq J, Birsen R, Johnson N, Deau Fischer B, Bouscary D, Kirova Y. Proton Therapy Reduces the Effective Dose to Immune Cells in Mediastinal Hodgkin Lymphoma Patients. Int J Part Ther, 13:100110, 2024. DOI: 10.1016/j.ijpt.2024.100110.

  16. Loap P, Vu-Bezin J, De Marzi L, Kirova Y. Proton therapy reduces the effective dose to immune cells in breast cancer patients. Strahlenther Onkol. in press, 2024. DOI: 10.1007/s00066-024-02263-1.

  17. Bertho A, Ortiz R, Maurin M, Juchaux M, Gilbert C, Espenon J, Ramasamy G, Patriarca A, De Marzi L, Pouzoulet F, Prezado Y. Thoracic Proton Minibeam Radiation Therapy: Tissue Preservation and Survival Advantage Over Conventional Proton Therapy. Int J Radiat Oncol Biol Phys, 120(2):579-592, 2024. DOI: 10.1016/j.ijrobp.2024.04.011.

  18. Massis H, Degombert MH, Dindart J, Lazard D, Trésallet C, Frouin F, Pillot-Loiseau C. Le rythme : un marqueur d’atteinte du nerf laryngé supérieur ? 35èmes Journées d'Études sur la Parole (JEP 2024) 31ème Conférence sur le Traitement Automatique des Langues Naturelles (TALN 2024) 26ème Rencontre des Étudiants Chercheurs en Informatique pour le Traitement Automatique des Langues (RECITAL 2024), Jul 2024, Toulouse, France. pp.461-469. https://inria.hal.science/hal-04623096

  19. Boellaard R*, Buvat I*, Nioche C, Ceriani L, Cottereau AS, Guerra L, Hicks RJ, Kanoun S, Kobe C, Loft A, Schöder H, Versari A, Coltin CA, Zwezerijnen GJC, Zijlstra JM, Mikhaeel NG, Gallamini A, El-Galaly TC, Hanoun C, Chauvie S, Ricci R, Zucca E, Meignan M, Barrington SF. International benchmark for total metabolic tumor volume measurement in baseline 18F-FDG PET/CT of lymphoma patients: a milestone towards clinical implementation. J Nucl Med, 65:1343-1348, 2024. DOI: 10.2967/jnumed.124.267789.

  20. Le TK, Comte V, Darcourt J, Razzouk-Cadet M, Rollet AC, Orlhac F, Humbert O. Performance and clinical impact of radiomics and 3D-CNN models for the diagnosis of neurodegenerative parkinsonian syndromes on [18F]-FDOPA PET. Clin Nuc Med, 
    49(10):924-930, 2024. DOI: 10.1097/RLU.0000000000005392.

  21. Captier N, Orlhac F, Hovhannisyan-Baghdasarian N, Luporsi M, Girard N, Buvat I. RadShap: an explanation tool for highlighting the contributions of multiple regions of interest to the prediction of radiomic models. J Nucl Med, 65:1307-1312, 2024. DOI: https://doi.org/10.2967/jnumed.124.267434

  22. Haberl D, Spielvogel CP, Orlhac F, Iommi D, Buvat I, Haug AR, Papp L. Multicenter PET Image Harmonization using Generative Adversarial Networks. Eur J Nucl Med Mol Imaging, 51:2532-2546, 2024. DOI: 10.1007/s00259-024-06708-8.

  23. Hovhannisyan-Baghdasarian N, Luporsi M, Captier N, Nioche C, Cuplov V, Woff E, Hegarat N, Livartowski A, Girard N, Buvat I, Orlhac F. New promising candidate prognostic biomarkers in [18F]FDG-PET images: evaluation in independent cohorts of NSCLC patients. J Nucl Med, 65:635-642, 2024. DOI: 10.2967/jnumed.123.266331

  24. Kocak B, Akinci D'Antonoli T, Mercaldo N, Alberich-Bavarri A, Baessler B, Ambrosini I, Andreychenko A, Bakas S, Beets-Tan R, Bressem K, Buvat I, Cannella R, Cappellini LA, Cavallo AU, Chepelev LL, Chu LCH, Demircioglu A, deSouza NM, Dietzel M, Fanni SC, Fedorov A, Fournier LS, Giannini V, Girometti R, Groot Lipman KBW, Kalarakis G, Kelly B, Klontas ME, Koh DM, Kotter E, Lee HY, Maas M, Marti-Bonmati L, Müller H, Obuchowski N, Orlhac F, Papanikolaou N, Petrash E, Pfaehler E, Pinto dos Santos D, Ponsiglione A, Sabater S, Sardanelli F, Seeböck P, Sijtema NM, Stanzione A, Traverso A, Ugga L, Vallières M, van Dijk LV, van Griethuysen JJM, van Hamersvelt RW, van Ooijen P, Vernuccio F, Wang A, Williams S, Witowski J, Zhang Z, Zwanenburg A, Cuocolo R. METhodological RadiomICs Score (METRICS): a quality scoring tool for radiomics research endorsed by EusoMII. Insights into Imaging, 15:8, 2024. DOI: https://doi.org/10.1186/s13244-023-01572-w 

  25. Fraioli F, Albert A, Boellaard R, Boscolo Galazzo I, Brendel M, Buvat I, Castellaro M, Cecchin D, Fernandez PA, Guedj E, Hammers A, Kaplar Z, Morbelli S, Papp L, Shi K, Tolboom N, Traub-Weidinger T, Verger A, Van Weehaeghe D, Yakushev I, Barthel M. Perspectives of the European Association of Nuclear Medicine on the role of artificial intelligence (AI) in molecular brain imaging. Eur J Nucl Med Mol Imaging, 51(4):1007-1011, 2024. DOI: 10.1007/s00259-023-06553-1

  26. Girum KB, Cottereau AS, Vercellino L, Rebaud L, Clerc J, Casasnovas O, Morschhauser F, Thieblemont C, Buvat I. Tumor location relative to the spleen is a prognostic factor in lymphoma patients: a demonstration from the REMARC trial. J Nucl Med, 65(2):313-319, 2024. DOI: 10.2967/jnumed.123.266322

  27. Cottereau AS , Rebaud L , Trotman J , Feugier P, Nastoupil LJ , Bachy E, Flinn IW, Haioun C,  Ysebaert L, Bartlett NL, Tilly H, Casasnovas O, Ricci R, Portugues C, Buvat I, Meignan M, Morschhauser F. Metabolic tumor volume predicts outcome in advanced stage follicular lymphoma patients from the Relevance trial. Ann Oncol, 35:130-137, 2024. DOI: https://doi.org/10.1016/j.annonc.2023.10.121

  28. Mahé M, Beddok A, Goudjil F, Ala Eddine C, Bolle S, Champion L, Feuvret L, Herman P, Zefkili S, Choussy O, Le Tourneau C, Dendale R, Buvat I, Sauvaget E, Créhange G, Calugaru V. Curative high-dose reirradiation for patients with recurrent head and neck adenoid cystic carcinomas: outcomes and analysis of patterns of failure. Int J Radiat Biol, 100:79-86, 2024. DOI: 10.1080/09553002.2023.2242934.

  29. Whybra P, Zwanenburg A, Andrearczyk V, Schaer R, Apte AP, Ayotte A, Baheti B, Bakas S, Bettinelli A, Boellaard R, Boldrini L, Buvat I, Cook GJR, Dietsche F, Dinapoli N, Gabryś HS, Goh V, Guckenberger M, Hatt M, Hosseinzadeh M, Iyer A, Lenkowicz J, Loutfi MAL, Löck A, Marturano A, Morin O, Nioche C, Orlhac F, Pati S, Rahmim A, Rezaeijo SM, Rookyard CG, Salmanpour MR, Schindele A, Shiri I, Spezi E, Tanadini-Lang S, Tixier F, Upadhaya T, Valentini V, van Griethuysen JJM, Yousefirizi F, Zaidi H,  Müller H, Vallières M, Depeursinge A. The Image Biomarker Standardization Initiative: Standardized Convolutional Filters for Reproducible Radiomics and Enhanced Clinical Insights. Radiology, 310: e231319, 2024. DOI: https://doi.org/10.1148/radiol.231319

Publications 2023

  1. Camoni L, Santos A, Luporsi M, Grilo A, Pietrzak A, Gear J, Zucchetta P, Bar-Sever Z. EANM procedural recommendations for managing the paediatric patient in diagnostic nuclear medicine. Eur J Nucl Med Mol Imaging, 50:3862-3879, 2023. DOI: doi: 10.1007/s00259-023-06357-3 

  2. Beddok A, Mouren V, Cottu P, Laki F, Fourquet A, Kirova Y. Outcomes and toxicity of concurrent CDK4/6 inhibitor and locoregional radiotherapy for patients with de novo metastatic breast cancer. Int J Cancer. 153(7):1386-1396, 2023. DOI: 10.1002/ijc.34562.  

  3. Beddok A, Chabi-Charvillat ML, Kennel T, de Wolf J, Pricopi C, Crequit P, Girard N, Otz J, Vallée A, Longchampt E, Sage E, Glorion M. Prospective Radiologic-Pathologic Correlation of Macroscopic Volume and Microscopic Extension of Nonsolid Lung Nodules on Thin-section CT Images for Sublobar Resection and Stereotactic Radiotherapy Planning. Clin Lung Cancer. 24(2):98-106, 2023. DOI: 10.1016/j.cllc.2022.11.001

  4. Schneider T, Malaise D, Pouzoulet F, Prezado Y. Orthovoltage X-ray Minibeam Radiation Therapy for the Treatment of Ocular Tumours-An In Silico Evaluation. Cancers (Basel). 15(3):679, 2023. DOI: 10.3390/cancers15030679

  5. Beddok A, Scher N, Alapetite C, Baussart B, Bentahila G, Bielle F, Bolle S, Dendale R, Dureau S, Goudjl F, Helfre S, Mammar H, Nichelli L, Calugaru V, Feuvret L. Proton therapy for adult craniopharyngioma: Experience of a single institution in 91 consecutive patients. Neuro Oncol. 25(4):710-719, 2023. DOI: 10.1093/neuonc/noac210.

  6. Deut U, Ronga MG, Bonfrate A, De Marzi L. Secondary radiation dose modeling in passive scattering and pencil beam scanning very high energy electron (VHEE) radiation therapy. Med Phys, 50(7):4491–4504, 2023. DOI: https://doi.org/10.1002/mp.16443

  7. Ronga MG, Deut U, Bonfrate A, De Marzi L. Very high-energy electron dose calculation using multiple scattering theory and a simplified pencil beam model. Med Phys, 1-14, 2023. DOI: https://doi.org/10.1002/mp.16697

  8. Flynn S, Allport P, De Marzi L, Green S, Homer M, Lee N, Ortiz R, Patriarca A, Prezado Y, Thomas R, Price T. Development of CMOS dosimetry in proton minibeams for enhanced QA and primary standard absorbed dose calorimetry. JINST, 8: P03014, 2023. DOI: https://doi.org/10.1088/1748-0221/18/03/P03014

  9. Leite AMM, Bonfrate A, Da Fonseca A, Lansonneur P, Alapetite C, Mammar H, De Marzi L. Double scattering and pencil beam scanning Monte Carlo workflows for proton therapy retrospective studies on radiation-induced toxicities. Cancer Radiother, S1278-3218(23)00070-7, 2023. DOI: https://doi.org/10.1016/j.canrad.2023.02.001

  10. Loap P, Barcellini A, De Marzi L, Orlandi E, Kirova Y. Neutron brachytherapy in the modern era: Indications and evidence. Cancer Radiother, 27(2):170–177, 2023. DOI: https://doi.org/10.1016/j.canrad.2022.08.010

  11. Seban RD, Arnaud E, Loirat D, Cabel L, Cottu P, Djerroudi L, Hescot A, Loap P, Bonneau C, Bidard FC, Huchet V, Jehanno N, Berenbaum A, Champion L, Buvat I. [18F]FDG PET/CT for predicting triple-negative breast cancer outcomes after neoadjuvant chemotherapy with or without pembrolizumab. Eur J Nucl Med Mol Imaging, 50:4024-4035, 2023.

  12. Malhaire C, Selhane F, Saint-Martin MJ, Cockenpot V, Akl P, Laas E, Bellesoeur A, Ala-Eddine C, Bereby-Kahane M, Manceau J, Sebbag-Sfez D, Pierga JY, Reyal F, Vincent-Salomon A, Brisse H, Frouin F. Exploring the added value of pretherapeutic MR descriptors in predicting breast cancer pathologic complete response to neoadjuvant chemotherapy. Eur Radiol, 33:8142-8154, 2023.

  13. Beddok A, Maynadier X, Krhili S, Ala Eddine C, Champion L, Chilles A, Goudjil F, Zefkili S, Amessis M, Choussy O, Le Tourneau C, Buvat I, Créhange G, Carton M, Calugaru V. Predictors of toxicity after curative reirradiation with intensity modulated radiotherapy or proton therapy for recurrent head and neck carcinoma: new dose constraints for pharyngeal constrictors muscles and oral cavity. Strahlenther Onkol,199:901-909, 2023.

  14. Kocak B, Baessler B, Bakas S, Cuocolo R, Fedorov A, Maier-Hein L, Mercaldo N, Müller H, Orlhac F,  Pinto dos Santos D, Stanzione A, Ugga L, Zwanenburg A. CheckList for EvaluAtion of Radiomics research (CLEAR): a step-by-step reporting guideline for authors and reviewers. Insights into Imaging, 14(1):75, 2023. DOI: 10.1186/s13244-023-01415-8

  15. Buvat I, Weber W. Nuclear Medicine from a Novel Perspective: Buvat and Weber Talk with OpenAI's ChatGPT. J Nucl Med. 64:505-507, 2023. DOI: 10.2967/jnumed.123.265636

  16. Khalid F, Goya-Outi J, Escobar T, Dangouloff-Ros V, Grigis A, Philippe C, Boddaert N, Grill J, Frouin V, Frouin F. Multimodal MRI radiomic models to predict genomic mutations in diffuse intrinsic pontine glioma with missing imaging modalitie. Front Med, 10:1071447, 2023, DOI: 10.3389/fmed.2023.1071447.

  17. Nanni C, Kobe C, Baessler B, Baues C, Boellaard R, Borchmann P, Buck A, Buvat I, Chapuy B, Cheson B, Chrzan R, Cottereau AS, Dührsen U, Eikenes L, Hutchings M, Jurczak W, Kraeber-Bodéré F, Kopci E, Luminari S, MacLennan S, Mikhaeel G, Nijland M, Rodriguez-Otero P, Treglia G, Withofs N, Zamagni E, Zinzani PL, Zijlstra JM, Herrmann K, Kunikowska J. EANM Focus 4: Consensus on molecular imaging and therapy in haematological tumors. Lancet Haematol, 10(5):e367-e381, 2023. DOI: 10.1016/S2352-3026(23)00030-3. 

  18. Saboury B, Bradshaw T, Boellaard R, Buvat I, Dutta J, Hatt M, Jha AK, Li Q, Liu C, McMeekin H, Morris MA, Scott PJH, Siegel E, Sunderland JJ, Wahl RL, Zuehlsdorff S, Rahmim A. Toward Trustworthy Artificial Intelligence Ecosystems: Opportunities, Challenges, and Responsibilities in Nuclear Medicine. J Nucl Med, 64:188-196, 2023. DOI: 10.2967/jnumed.121.263703.  

  19. Rahimpour M, Saint Martin MJ, Frouin F, Akl P, Orlhac F, Koole M, Malhaire C. Visual ensemble selection of deep convolutional neural networks for 3D segmentation of breast tumors on dynamic contrast enhanced MRI. Eur Radiol, 33(2):959-969, 2023. DOI: 10.1007/s00330-022-09113-7

  20. Beddok A, Orlhac F, Calugaru V, Champion L, Ala Eddine C, Nioche C, Crehange G, Buvat I. [18F]-FDG PET and MRI radiomic signatures to predict the risk and the location of tumor recurrence after re-irradiation in head and neck cancer. Eur J Nucl Med Mol Imaging, 50(2):559-571, 2023. DOI: 10.1007/s00259-022-06000-7

  21. Ortiz R, Belshi R, De Marzi L, Prezado Y. Proton minibeam radiation therapy for treating metastases: a treatment plan study. Medical Physics, 10.1002/mp.16203, 2023. DOI: 10.1002/mp.16203

  22. Leite AMM, Cavallone M, Ronga MG, Trompier F, Patriarca A, De Marzi L. Ion recombination correction factors and benchmark of detectors in a very-high dose rate proton scanning beam. Physica Medica, 106:102518, 2023. DOI: https://doi.org/10.1016/j.ejmp.2022.102518

  23. Iturri L, Bertho A, Lamirault C, Juchaux M, Gilbert C, Espenon J, Sebrie C, Jordain L, Pouzoulet F, Verrelle P, de Marzi L, Prezado Y. Proton flash therapy and immune infiltration: evaluation in an orthotopic glioma rat model. Int J Rad Oncol Biol Physics, 116:655-665, 2023. DOI: https://doi.org/10.1016/j.ijrobp.2022.12.018

  24. Guardiola C, Bachiller-Perea D, Kole EMM, Fleta C, Quirion D, De Marzi L, Gómez F. First experimental measurements of 2D microdosimetry maps in proton therapy. Med Phys. 50(1):570-581, 2023. DOI: 10.1002/mp.15945 

Publications 2022

  1. Saint Martin MJ, Frouin F, Malhaire C, Orlhac F. Decrypting the information captured by MRI-radiomic features in predicting the response to neoadjuvant chemotherapy in breast cancer. 44th Annual International Conference of the IEEE Engineering in Medicine & Biology Society (EMBC), 3227-3230, 2022. DOI: 10.1109/EMBC48229.2022.9871844.

  2. Thomas CD, Lupu M, Poyer F, Maillard P, Mispelter J. Increased PDT efficacy when associated with nitroglycerin: a study of retinoblastoma xenografts on mice. Pharmaceuticals, 15(8):985, 2022. DOI: 10.3390/ph15080985

  3. Beddok A, Saint-Martin C, Ala Eddine C, Champion L, Krhili S, Chilles A, Catteau L, Goudjil F, Zefkili S, Amessis M, Peurien D, Choussy O, Le Tourneau C, Klijanienko J, Dendale R, Buvat I , Créhange G, Calugaru V. Curative high-dose reirradiation for patients with recurrent head and neck squamous cell carcinoma using IMRT or proton therapy: Outcomes and Analysis of patterns of failure. Head & Neck, 44(11):2452-2464, 2022. DOI: 10.1002/hed.27153

  4. Beddok A, Guzene L, Coutte A, Thomson D, Yom SS, Calugaru V, Blais E, Gilliot O, Racadot S, Pointreau Y, Corry J, Jensen K, Porceddu S, Khalladi N, Bastit V, Lasne-Cardon A, Marcy PY, Carsuzaa F, Nioche C, Bourhis J, Salleron J, Thariat J; GORTEC. International assessment of interobserver reproducibility of flap delineation in head and neck carcinoma. Acta Oncol. 61(6):672-679, 2022. DOI: 10.1080/0284186X.2022.2036367.

  5. Guzene L, Beddok A, Nioche C, Modzelewski R, Loiseau C, Salleron J, Thariat J. Assessing Interobserver Variability in the Delineation of Structures in Radiation Oncology: A Systematic Review. Int J Radiat Oncol Biol Phys. S0360-3016(22)03551-9, 2022. DOI: 10.1016/j.ijrobp.2022.11.021.

  6. Beddok A, Lahaye C, Calugaru V, De Marzi L, Fouillade C, Salvador S, Fontbonne JM, Favaudon V, Thariat J. A Comprehensive Analysis of the Relationship Between Dose Rate and Biological Effects in Preclinical and Clinical Studies, From Brachytherapy to Flattening Filter Free Radiation Therapy and FLASH Irradiation. Int J Radiat Oncol Biol Phys. 113(5):985-995, 2022. DOI: 10.1016/j.ijrobp.2022.02.009

  7. Porte J, Saint-Martin C, Frederic-Moreau T, Massiani MA, Bozec L, Cao K, Verrelle P, Otz J, Jadaud E, Minsat M, Langer A, Girard N, Créhange G, Beddok A. Efficacy and Safety of Combined Brain Stereotactic Radiotherapy and Immune Checkpoint Inhibitors in Non-Small-Cell Lung Cancer with Brain Metastases. Biomedicines. 10(9):2249, 2022. DOI: 10.3390/biomedicines10092249

  8. Beddok A, Scher N, Alapetite C, Baussart B, Bentahila G, Bielle F, Bolle S, Dendale R, Dureau S, Goudjl F, Helfre S, Mammar H, Nichelli L, Calugaru V, Feuvret L. Protontherapy for adult craniopharyngioma: experience of a single institution in 91 consecutive patients. Neuro Oncol. In press, 2022. DOI: 10.1093/neuonc/noac210

  9. Beddok A, Chabi-Charvillat ML, Kennel T, de Wolf J, Pricopi C, Crequit P, Girard N, Otz J, Vallée A, Longchampt E, Sage E, Glorion M. Prospective Radiologic-Pathologic Correlation of Macroscopic Volume and Microscopic Extension of Nonsolid Lung Nodules on Thin-section CT Images for Sublobar Resection and Stereotactic Radiotherapy Planning. Clin Lung Cancer. 2022 Nov 9:S1525-7304(22)00243-1. DOI: 10.1016/j.cllc.2022.11.001.

  10. Bauer J, Hildebrandt M, Baumgartl M, Fiedler F, Robert C, Buvat I,  Enghardt W, Parodi K. Quantitative assessment of radionuclide production yields in in-beam and offline PET measurements at different proton irradiation facilities. Phys Med Biol, 14;67(15). DOI : 10.1088/1361-6560/ac7a89.

  11. Durmo R, Donati B, Rebaud L, Cottereau AS, Ruffini A, Nizzoli M, Ciavarella S, Vegliante M, Nioche C, Meignan M, Merli F, Versari A, Ciarrocchi A, Buvat I, Luminari S. Prognostic value of lesion dissemination in ABVD-treated, iPET-negative cHL patients: a radio-genomic study. Hemat Oncol. 40(4):645-657, 2022. DOI: 10.1002/hon.3025 

  12. Jha AK, Bradshaw TJ, Buvat I, Hatt M, Kc P, Liu C, Obuchowski NF, Saboury B, Slomka PJ, Sunderland JJ, Wahl RL, Yu Z, Zuehlsdorff S, Rahmim A, Boellaard R. Nuclear Medicine and Artificial Intelligence: Best Practices for Evaluation (the RELAINCE guidelines). J Nucl Med. 63: 1288-1299, 2022. DOI: https://doi.org/10.2967/jnumed.121.263239 

  13. Guesdon-Vennerie A, Couvreur P, Ali F, Pouzoulet F, Roulin C, Martínez-Rovira I, Bernadat G, Legrand FX, Bourgaux C, Mazars C, Marco S, Trépout S, Mura S, Mériaux S, Bort G. Breaking photoswitch activation depth limit using ionising radiation stimuli adapted to clinical application. Nat Comm. 13(1):4102. DOI: 10.1038/s41467-022-30917-0

  14. Girum KB, Rebaud L, Cottereau AS, Meignan M, Clerc J, Vercellino L, Casasnovas O, Morschhauser F, Thieblemont C, Buvat I. 18F-FDG PET maximum intensity projections and artificial intelligence: a win-win combination to easily measure prognostic biomarkers in DLBCL patients. J Nucl Med 63(12):1925-1932, 2022. DOI :10.2967/jnumed.121.263501.

  15. Kolinger GD, García DV, Kramer GM, Frings V, Zwezerijnen GJC, Smit EF, De Langen AJ, Buvat I, Boellaard R. Effects of tracer uptake time in non-small cell lung cancer 18F-FDG PET radiomics. J Nucl Med. 63(6):919-924, 2022. DOI: 10.2967/jnumed.121.262660

  16. Comte V, Schmutz H, Humbert O, Orlhac F, Chardin D, Darcourt J. Development and validation of a radiomic model for the diagnosis of dopaminergic denervation on [18F]FDOPA PET/CT. Eur J Nucl Med Mol Imaging. 49(11):3787-3796. 2022. DOI: 10.1007/s00259-022-05816-7

  17. Peltier A, Seban R, Buvat I, Bidard FC, Mechta-Grigoriou F. Fibroblast heterogeneity in solid tumors: from single cell analysis to whole-body imaging. Semin Cancer Biol. 86(Pt3):262-272, 2022. DOI: 10.1016/j.semcancer.2022.04.008

  18. Dal Toso L, Chalampalakis Z, Buvat I, Comtat C, Cook G, Goh V, Schnabel JA, Marsden PK. Improved 3D Tumour Definition and Quantification of Uptake in Simulated Lung Tumours Using Deep Learning. Phys Med Biol. 67:095013, 2022. DOI: 10.1088/1361-6560/ac65d6

  19. Bradshaw TJ, Boellaard R, Dutta J, Jha AK, Jacobs P, Li Q, Liu C, Sitek A, Saboury B, Scott PJH, Slomka PJ, Sunderland JJ, Wahl RL, Yousefirizi F, Zuehlsdorff S, Rahmim A, Buvat I. Nuclear Medicine and Artificial Intelligence: Best Practices for Algorithm Development. J Nucl Med. 63(4):500-510, 2022. DOI: https://doi.org/10.2967/jnumed.121.262567 

  20. Créhange G, Goudjil F, Krhili SL, Minsat M, de Marzi L, Dendale R. The role of proton therapy in esophageal cancer. Cancer radiotherapie 26(4):602-610, 2022. DOI: https://doi.org/10.1016/j.canrad.2021.08.015

  21. Beddok A, Calugaru V, de Marzi L, Graff P, Dumas JL, Goudjil F, Dendale R, Minsat M, Verrelle P, Buvat I, Créhange G. Clinical and technical challenges of cancer reirradiation: Words of wisdom. Crit Rev Oncol Hematol. 174:103655, 2022. DOI: 10.1016/j.critrevonc.2022.103655

  22. Ortiz R, De Marzi L, Prezado Y. Proton Minibeam Radiation Therapy and Arc Therapy: Proof of Concept of a Winning Alliance. Cancers (Basel). 14(1):116, 2022. DOI: 10.3390/cancers14010116.

  23. Escobar T, Vauclin S, Orlhac F, Nioche C, Pineau P, Champion L, Brisse H, Buvat I. Voxel-wise supervised analysis of tumors with multimodal engineered features to highlight interpretable biological patterns. Med Phys. 49(6):3816-3829, 2022. DOI: 10.1002/mp.15603

  24. Wallis D, Buvat I. Clever Hans effect found in a widely used brain tumour MRI dataset. Med Image Anal. 77:102368, 2022. DOI: 10.1016/j.media.2022.102368

  25. Loap P, Mirandola A, De Marzi L, Vitolo V, Barcellini A, Iannalfi A, Dendale R, Kirova Y, Orlandi E. Cardiac conduction system exposure with modern radiotherapy techniques for mediastinal Hodgkin lymphoma irradiation (Letter). Acta Oncol. 11:1-4, 2022. DOI: 10.1080/0284186X.2021.2025265.

  26. Seban RD, Champion L, Muneer I, Synn S, Schwartz LH, Dercle L. Potential theranostic role of bone marrow glucose metabolism on baseline [18F]-FDG PET/CT in metastatic melanoma (letter to the Editor). J Nucl Med. 63:166, 2022. DOI: 10.2967/jnumed.121.262361

  27. Cardoen L, Tauziède-Espariat A, Dangouloff-Ros V, Moalla S, Nicolas N, Roux CJ, Bouchoucha Y, Bourdeaut F, Beccaria K, Bolle S, Pierron G, Dufour C, Doz F, Boddaert N, Brisse HJ. Imaging Features with Histopathologic Correlation of CNS High-Grade Neuroepithelial Tumors with a BCOR Internal Tandem Duplication. AJNR Am J Neuroradiol. 43:151-156, 2022. DOI: 10.3174/ajnr.A7367.

  28. Orlhac F, Eertink JJ, Cottereau AS, Zijlstra JM, Thieblemont C, Meignan M, Boellaard R, Buvat I. A guide to ComBat harmonization of imaging biomarkers in multi center studies. J Nucl Med. 63(2):172-179, 2022. DOI: https://doi.org/10.2967/jnumed.121.262464 

  29. Wallis D, Soussan M, Lacroix M, Akl P, Duboucher C, Buvat I. An FDG-PET/CT deep learning method for fully automated detection of pathological mediastinal lymph nodes in lung cancer patients. Eur J Nucl Med Mol Imaging. 49(3):881-888, 2022. DOI: https://doi.org/10.1007/s00259-021-05513-x

  30. Hahn C, Ödén J, Dasu A, Vestergaard A, Fuglsang Jensen M, Sokol O, Pardi C, Bourhaleb F, Leite A, de Marzi L, Smith E, Aitkenhead A, Rose C, Merchant M, Kirkby K, Grzanka L, Pawelke J, Lühr A. Towards harmonizing clinical linear energy transfer (LET) reporting in proton radiotherapy: a European multi-centric study. Acta oncologica, 61:206-214, 2022. DOI:  https://doi.org/10.1080/0284186X.2021.1992007

  31. Cavallone M, Prezado Y, De Marzi L. Converging Proton Minibeams with Magnetic Fields for Optimized Radiation Therapy: A Proof of Concept. Cancers (Basel). 14(1):26, 2022. DOI: 10.3390/cancers14010026

  32. Loap P, De Marzi L, Almeida CE, Barcellini A, Bradley J, de Santis MC, Dendale R, Jimenez R, Orlandi E, Kirova Y. Hadrontherapy techniques for breast cancer. Crit Rev Oncol Hematol. 169:103574, 2022. DOI: https://doi.org/10.1016/j.critrevonc.2021.103574.

  33. Perret P, Slimani L, Barone-Rochette G, Vollaire J, Briat A, Ahmadi M, Henri M, Desruet MD, Clerc R, Broisat A, Riou L, Boucher F, Frouin F, Djaileb L, Calizzano A, Vanzetto G, Fagret D, Ghezzi, C. Preclinical and clinical evaluation of a new method to assess cardiac insulin resistance using nuclear imaging. J Nucl Cardiol. 29:1419–1429, 2022. DOI: 10.1007/s12350-020-02520-7

  34. Seban RD, Richard C, Nascimento-Leite C, Ghidaglia J, Provost C, Gonin J, Le Tourneau C, Romano E, Deleval N, Champion L. Absolute lymphocyte count after COVID-19 vaccination is associated with vaccine-induced hypermetabolic lymph nodes on 18F-FDG PET/CT: a focus in breast cancer care. J Nucl Med. 63: 1231-1238, 2022. DOI: 10.2967/jnumed.121.263082.

Publications 2021

  1. Ortiz R, De Marzi L, Prezado Y. Proton Minibeam Radiation Therapy and Arc Therapy: Proof of Concept of a Winning Alliance. Cancers (Basel). 14(1):116, 2021. DOI: 10.3390/cancers14010116.

  2. Cavallone M, Prezado Y, De Marzi L. Converging Proton Minibeams with Magnetic Fields for Optimized Radiation Therapy: A Proof of Concept. Cancers (Basel). 14(1):26, 2021. DOI: 10.3390/cancers14010026.

  3. Beddok A, Cottu P, Fourquet A, Kirova Y. Combination of modern radiotherapy and new targeted treatments for breast cancer management. Cancers 13(24):6358, 2021. DOI: 10.3390/cancers13246358.

  4. Chegraoui H, Philippe C, Dangouloff-Ros V, Grigis A, Calmon R, Boddaert N,  Frouin F, Grill J, Frouin V. Object detection improves tumour segmentation in MR images of rare brain tumours. Cancers 13(23): 6113, 2021. DOI: https://doi.org/10.3390/cancers13236113

  5. Loap P, Vischioni B, Bonora M, Ingargiola R, Ronchi S, Vitolo V, Barcellini A, Goanta L, De Marzi L, Dendale R, Pacelli R, Locati L, Calugaru V, Mammar H, Cavalieri S, Kirova Y, Orlandi E. Biological Rationale and Clinical Evidence of Carbon Ion Radiation Therapy for Adenoid Cystic Carcinoma: A Narrative Review. Front Oncol. 11:789079, 2021. DOI: 10.3389/fonc.2021.789079.

  6. El Beheiry M, Gaillard T, Girard N, Darrigues L, Osdoit M, Feron JG, Sabaila A, Laas E, Fourchotte V, Laki F, Lecuru F, Couturaud B, Binder JP, Masson JB, Reyal F, Malhaire C. Breast Magnetic Resonance Image Analysis for Surgeons Using Virtual Reality: A Comparative Study. JCO Clin Cancer Inform. 5:1127-1133, 2021. DOI: 10.1200/CCI.21.00048.

  7. Maia Leite A, Ronga MG, Giorgi M, Ristic Y, Perrot Y, Trompier F, Prezado Y, Créhange G, De Marzi L. Secondary neutron dose contribution from pencil beam scanning, scattered and spatially fractionated proton therapy. Phys Med Biol, 66: 225010, 2021. DOI: https://doi.org/10.1088/1361-6560/ac3209

  8. Ronga MG, Cavallone M, Patriarca A, Leite AM, Loap P, Favaudon V, Créhange G, De Marzi L. Back to the Future: Very High-Energy Electrons (VHEEs) and Their Potential Application in Radiation Therapy. Cancers. 13:4942, 2021. DOI: https://doi.org/10.3390/cancers13194942

  9. Bertho A, Ortiz R, Juchaux M, Gilbert C, Lamirault C, Pouzoulet F, Polledo L, Liens A, Warfving N, Sebrie C, Jourdain L, Patriarca A, de Marzi L, Prezado Y. First Evaluation of Temporal and Spatial Fractionation in Proton Minibeam Radiation Therapy of Glioma-Bearing Rats. Cancers. 13(19):4865, 2021. DOI: https://doi.org/10.3390/cancers13194865

  10. Loap P, Vitolo V, Barcellini A, De Marzi L, Mirandola A, Fiore MR, Vischioni B, Jereczek-Fossa BA, Girard N, Kirova YM, Orlandi E. Hadrontherapy for thymic epithelial tumors: implementation in clinical practice. Front. Oncol. 11:738320, 2021. DOI: https://doi.org/10.3389/fonc.2021.738320

  11. Wimberley C, Buvat I, Boutin H. Imaging translocator protein expression with Positron Emission Tomography. Eur J Nucl Med Mol Imaging. 49:74-75, 2021. DOI: 10.1007/s00259-021-05601-y

  12. Sabra D, Intzandt B, Desjardins-Crépeau L, Langeard A, Steele CJ, Frouin F, Hoge RD, Bherer L, Gauthier C. Sex moderates the relationship between aortic stiffness, cognition, and cerebrovascular reactivity in healthy older adults.  PLoS One. 16(9):e0257815, 2021. DOI: 10.1371/journal.pone.0257815

  13. Peters N, Wohlfahrt P, Dahlgren CV, de Marzi L, Ellerbrock M, Fracchiolla F, Freeh J, Gomà C, Góra J, Jensen MF, Kajdrowicz T, Mackay R, Molinelli S, Rinaldi I, Rompokos V, Siewert D, van der Tol P, Vermeren X, Nyström H, Lomax A, Richter C. Experimental assessment of inter-centre variation in stopping-power and range prediction in particle therapy. Radiother Oncol. 163:7-13, 2021. DOI: https://doi.org/10.1016/j.radonc.2021.07.019

  14. Loap P, Mirandola A, De Marzi L, Dendale R, Iannalfi A, Vitolo V, Barcellini A, Filippi AR, Jereczek-Fossa BA, Kirova Y, Orlandi E. Current Situation of Proton Therapy for Hodgkin Lymphoma: from Expectations to Evidence. Cancers 13: 3746, 2021. DOI: https://doi.org/10.3390/cancers13153746 

  15. Loap P, De Marzi L, Mirandola A, Dendale R, Iannalfi A, Vitolo V, Barcellini A, Filippi AR, Jereczek-Fossa BA, Kirova Y, Orlandi E. Development and Implementation of Proton Therapy for Hodgkin Lymphoma: Challenges and Perspectives. Cancers, 13:3744, 2021. DOI: https://doi.org/10.3390/cancers13153744

  16. Vidal M, Moignier C, Patriarca A, Sotiropoulos M, Schneider T, De Marzi L. Future technological developments in proton therapy - a predicted technological breakthrough. Cancer Radiother. 25:554-564, 2021. DOI: https://doi.org/10.1016/j.canrad.2021.06.017

  17. Malaise D, Houillier C, Touitou V, Choquet S, Maloum K, Le Garff-Tavernier M, Davi F, Vincent-Salomon A, Feuvret L, Hoang-Xuan K, Cassoux N, Soussain C. LOC network and the ERN-EuroBloodNet. Primary vitreoretinal lymphoma: short review of the literature, results of a European survey and French guidelines of the LOC network for diagnosis, treatment and follow-up. Curr Opin Oncol. 33:420-431, 2021. DOI: 10.1097/CCO.0000000000000776.

  18. Soussain C, Malaise D, Cassoux N. Primary vitreoretinal lymphoma: A diagnostic and management challenge. Blood. 2021 May 25:blood.2020008235. DOI: 10.1182/blood.2020008235.  

  19. Jehan-Besson S, Clouard R, Boddaert N, Grill J, Frouin F. Optimization of a Shape Metric Based on Information Theory Applied to Segmentation Fusion and Evaluation in Multimodal MRI for DIPG Tumor Analysis. Proceedings of 5th International Conference GSI 2021: 772-780. DOI: 10.1007/978-3-030-80209-7_83

  20. Cottereau AS, Meignan M, Nioche C, Clerc J, Chartier L, Vercellino L, Casasnovas O, Thieblemont C, Buvat I. New approaches in characterisation of lesions dissemination in DLBCL patients on baseline PET/CT. Cancers. 13:3998, 2021. DOI: https://doi.org/10.3390/cancers13163998 

  21. Seban RD, Donnadieu A, Journo G, Bidard FC, Richard C, Rouzier R, Champion L.18F-FDG PET/CT in Relapsed Endometrial Cancer Treated with Preoperative PD-1 Inhibitor Dostarlimab. Diagnostics. 11:1353, 2021. DOI: https://doi.org/10.3390/diagnostics11081353

  22. Seban RD, Synn S, Muneer I, Champion L, Schwartz LH, Dercle L. Spleen Glucose Metabolism on [18F]-FDG PET/CT for Cancer Drug Discovery and Development cannot be Overlooked. Curr Cancer Drug Targets. 21:944-952, 2021. DOI: 10.2174/1568009621666210720143826.

  23. Seban RD, Assié JB, Giroux-Leprieur E, Massiani MA, Bonardel G, Chouaid C, Deleval N, Richard C, Mezquita L, Girard N, Champion L. Prognostic value of inflammatory response biomarkers using peripheral blood and [18F]-FDG PET/CT in advanced NSCLC patients treated with first-line chemo- or immunotherapy. Lung Cancer. 159: 45-55, 2021. DOI: https://doi.org/10.1016/j.lungcan.2021.06.024 

  24. Orlhac F, Nioche C, Klyuzhin I, Rahmim A, Buvat I. Radiomics in PET imaging - A practical guide for newcomers. PET Clin. 16(4):597-612, 2021. DOI: 10.1016/j.cpet.2021.06.007

  25. Seban RD, Champion L, Yeh R, Schwartz LH, Dercle L. Assessing immune response upon systemic RNA vaccination on [18F]-FDG PET/CT for COVID-19 vaccine and then for immune-oncology? (letter to the Editor). Eur J Nucl Med Mol Imaging. 48:3351-3352, 2021. DOI: 10.1007/s00259-021-05468-z

  26. Dumas JL, Dal R, Zefkili S, Robilliard M, Losa S, Birba I, Vu-Bezin J, Beddok A, Calugaru V, Dutertre G, De Marzi L. Addressing the dosimetric impact of bone cement and vertebroplasty in stereotactic body radiation therapy. Phys Med. 85:42-49, 2021. DOI: 10.1016/j.ejmp.2021.04.023.

  27. Costa E, Richir T, Robilliard M, Bragard C, Logerot C, Kirova Y, Fourquet A, De Marzi L. Assessment of a conventional volumetric-modulated arc therapy knowledge-based planning model applied to the new Halcyon© O-ring linac in locoregional breast cancer radiotherapy. Phys Med. 86:32-43. 2021. DOI: 10.1016/j.ejmp.2021.05.022.  

  28. Orlhac F, Buvat I. Comment on Ibrahim, A. et al. The Effects of In-Plane Spatial Resolution on CT-Based Radiomic Features’ Stability with and without ComBat Harmonization. Cancers. 13(12): 3037, 2021. DOI: https://doi.org/10.3390/cancers13123037 

  29. Seban RD, Vermersch C, Champion L, Bonsang B, Roger A, Ghidaglia J. Immune-Related Erythema Nodosum Mimicking in Transit Melanoma Metastasis on [18F]-FDG PET/CT. Diagnostics. 11: 747, 2021. DOI: https://doi.org/10.3390/diagnostics11050747

  30. Aide N, Lasnon C, Kesner A, Levin C, Buvat I, Iagaru A, Hermann K, Badawi RD, Cherry SR, Bradley KM, McGowan DR. New PET technologies: embracing progress and pushing the limits. Eur J Nucl Med Mol Imaging. 48: 2711–2726, 2021. DOI: https://doi.org/10.1007/s00259-021-05390-4

  31. Beyer T, Bailey DL, Birk UJ, Buvat I, Catana C, Cheng Z, Fang Q, Giove F, Kuntner C, Laistler E, Moscato F, Nekolla SG, Rausch I, Ronen I, van Elmpt W, Saarakkala S, Thielemans K, Moser E. Medical Physics and Imaging – A timely perspective. Frontiers in Physics. 9:634693, 2021. DOI: https://doi.org/10.3389/fphy.2021.634693

  32. Seban RD, Champion L, Deleval N, Richard C, Provost C. Immune Response Visualized In Vivo by [18F]-FDG PET/CT after COVID-19 Vaccine. Diagnostics. 11: 676, 2021. DOI: https://doi.org/10.3390/diagnostics11040676

  33. Seban RD, Rouzier R, Latouche A, Deleval N, Guinebretiere JM, Buvat I, Bidard FC, Champion L. Total metabolic tumor volume and spleen metabolism on baseline [18F]-FDG PET/CT as independent prognostic biomarkers of recurrence in resected breast cancer. Eur J Nucl Med Mol Imaging. 48: 3560-3570, 2021. DOI: https://doi.org/10.1007/s00259-021-05322-2 

  34. Schneider T, De Marzi L, Patriarca A and Prezado Y. Monte Carlo Comparison of Proton and Helium-ion Minibeam Generation Techniques. Front. Phys. 9:595721, 2021. DOI: https://doi.org/10.3389/fphy.2021.595721

  35. Loto O, Zahradnik I, Leite AM, De Marzi L, Tromson D, Pomorski M. Simultaneous measurements of dose and microdosimetric spectra in a clinical proton beam using a scCVD diamond membrane microdosimeter. Sensors (Basel). 21:1314, 2021. DOI: https://www.mdpi.com/1424-8220/21/4/1314

  36. Leduc A, Chaouni S, Pouzoulet F, De Marzi L, Megnin-Chanet F, E Corre, Stefan D, Habrand JL, Sichel F, Laurent C. Differential normal skin transcriptomic response in total body irradiated mice exposed to scattered versus scanned proton beams. Sci Rep 11, 5876, 2021. DOI: https://doi.org/10.1038/s41598-021-85394-0

  37. Buvat I, Orlhac F. The T.R.U.E. checklist for identifying impactful AI-based findings in nuclear medicine: is it True? Is it Reproducible? Is it Useful? Is it Explainable? J Nucl Med. 62: 752-754, 2021. DOI: https://doi.org/10.2967/jnumed.120.261586 

  38. Prezado Y, Hirayama R, Matsufuji N, Inaniwa T, Martínez-Rovira I, Seksek O, Bertho A, Koike S, Labiod D, Pouzoulet F, Polledo L, Warfving N, Liens A, Bergs J, Shimokawa T. A potential renewed use of very heavy ions for therapy: Neon minibeam radiation therapy. Cancers. 13:1356, 2021. DOI: 10.3390/cancers13061356

  39. Weber M, Kersting D, Umutlu L, Schäfers M, Rischpler C, Fendler WP, Buvat I, Herrmann K, Seifert R. Just another ‘Clever Hans’? Neural Networks and FDG PET‑CT to predict the Outcome of Patients with Breast Cancer. Eur J Nucl Med Mol Imaging. 48: 3141-3150, 2021. DOI: 10.1007/s00259-021-05270-x

  40. Seban RD, Champion L, Schwartz LH, Dercle L. Spleen glucose metabolism on [F-18]-FDG PET/CT: a dynamic double-edged biomarker predicting outcome in cancer patients (letter to the Editor). Eur J Nucl Med Mol Imaging. 48: 2309-2311, 2021. DOI: 10.1007/s00259-020-05126-w

  41. Saint Martin MJ, Orlhac F, Akl P, Khalid F, Nioche C, Buvat I, Malhaire C, Frouin F. A radiomics pipeline dedicated to Breast MRI: validation on a multi-scanner phantom study. MAGMA. 34: 355-366, 2021. DOI: 10.1007/s10334-020-00892-y

  42. Cottereau AS, Meignan M, Nioche C, Capobianco N, Clerc J, Chartier L, Vercellino L, Casasnovas O, Thieblemont C, Buvat I. Risk stratification in diffuse large B cell lymphoma using lesion dissemination and metabolic tumor burden calculated from baseline PET/CT. Ann Oncol. 32: 404-411, 2021. DOI: 10.1016/j.annonc.2020.11.019

  43. Sundar LKS , Muzik O, Buvat I, Bidaut L, Beyer T. Potentials and caveats of artificial intelligence in hybrid imaging. Methods. 188: 4-19, 2021. DOI: 10.1016/j.ymeth.2020.10.004

  44. Orlhac F, Lecler A, Savatovski J, Goya-Outi J, Nioche C, Charbonneau F, Ayache N, Frouin F, Duron L, Buvat I. How can we combat multicenter variability in MR radiomics? Validation of a correction procedure. Eur Rad. 31: 2272-2280, 2021. DOI: 10.1007/s00330-020-07284-9

  45. Capobianco N, Meignan M, Cottereau AS, Vercellino L, Sibille L, Spottiswoode B, Zuehlsdorff S, Casasnovas O, Thieblemont C, Buvat I. Deep learning FDG uptake classification enables total metabolic tumor volume estimation in diffuse large B-cell lymphoma. J Nucl Med. 62: 30-36, 2021. DOI: 10.2967/jnumed.120.242412

Publications 2020

  1. Chaouni S, Leduc A, Pouzoulet F, De Marzi L, Megnin-Chanet F, Stefan D, Habrand J-L, Sichel F, Laurent C. Biological Effects of Scattered Versus Scanned Proton Beams on Normal Tissues in Total Body Irradiated Mice: Survival, Genotoxicity, Oxidative Stress and Inflammation. Antioxidants. 9:1170, 2020.

  2. Weber WA, Czernin J, Anderson CJ, Badawi RD, Bartel H, Bengel F, Bodei L, Buvat I, DiCarli M, Graham MM, Grimm J, Herrmann K, Kostakoglu L, Lewis JS, Peterson T, Schelbert H, Schoder H, Siegel BA, Strauss HW, Townsend DM. The future of nuclear medicine, molecular imaging, and theranostics. J Nucl Med. 61: 263S-272S, 2020. DOI: 10.2967/jnumed.120.254532

  3. Lamirault C, Doyère V, Juchaux M, Pouzoulet F, Labiod D, Dendale R, Patriarca A, Nauraye C, Le Dudal M, Jouvion G, Hardy D, Massioui NE, Prezado Y. Short and long term evaluation of the impact of proton mini beam radiation therapy on motor, emotional and cognitive functions. Sci Rep. 10:13511, 2020. DOI: 10.1038/s41598-020-70371-w

  4. Wimberley C, Nguyen DL, Truillet C, Peyronneau MA, Gulhan Z, Tonietto M, Boumezbeur F, Boisgard R, Chalon S, Bouilleret V, Buvat I. Longitudinal mouse-PET imaging: a reliable method for estimating binding parameters without a reference region or blood sampling. Eur J Nucl Med Mol Imaging. 47:2589-2601, 2020. DOI: 10.1007/s00259-020-04755-5

  5. Zwanenburg A, Vallières M, Abdalah MA, Aerts HJWL, Andrearczyk V, Apte A, Ashrafinia S, Bakas S, Beukinga RJ, Boellaard R, Bogowicz M, Boldrini L, Buvat I, Cook GJR, Davatzikos C, Depeursinge A, Desseroit MC, Dinapoli N, Dinh CV, Echegaray V, El Naqa I, Fedorov AY, Gatta R, Gillies RJ, Goh V, Guckenberger M, Götz M, Ha SM, Hatt M, Isensee F, Lambin P, Leger S, Leijenaar RTH, Lenkowicz J, Lippert F, Losnegård A, Maier-Hein KH, Morin O, Müller H, Napel S, Nioche C, Orlhac F, Pati S, Pfaehler EAG, Rahmim A, Rao AUK, Scherer J, Siddique MM, Sijtsema NM, Fernandez JS, Spezi E, Steenbakkers RJHM, Tanadini-Lang S, Thorwarth D, Troost EGC, Upadhaya T, Valentini C, van Dijk LV, van Griethuysen J, van Velden FHP, Whybra P, Richter C, Löck S. The Image Biomarker Standardization Initiative: standardized quantitative radiomics for highthroughput image-based phenotyping. Radiology. 295:328-338, 2020. DOI: 10.1148/radiol.2020191145

  6. Lemaître S, Poyer F, Fréneaux P, Leboucher S, Doz F, Cassoux N, Thomas CD. Low retinal toxicity of intravitreal carboplatin associated with good retinal tumour control in transgenic murine retinoblastoma. Clin Exp Ophthalmol. 48:500-511, 2020. DOI: 10.1111/ceo.13711

  7. Tanaka I, Chakraborty A, Saulnier O, Benoit-Pilven C, Vacher S, Labiod D, Lam EWF, Bièche I, Delattre O, Pouzoulet F, Auboeuf D, Vagner S, Dutertre M. ZRANB2 and SYF2-mediated splicing programs converging on ECT2 are involved in breast cancer cell resistance to doxorubicin. Nucleic Acids Res. 2020. DOI: 10.1093/nar/gkz1213

  8. Lacroix M, Frouin F, Dirand AS, Nioche C, Orlhac F, Bernaudin JF, Brillet PY, Buvat I. Correction for magnetic field inhomogeneities and normalization of voxel values are needed to better reveal the potential of MR radiomic features in lung cancer. Front Oncol. doi: 10.3389/fonc.2020.00043, 2020. DOI: 10.3389/fonc.2020.00043

  9. Cottereau AS, Nioche C, Dirand AS, Clerc J, Morschhauser F, Casasnovas O, Meignan MA, Buvat I. 18F-FDG-PET dissemination features in diffuse large B cell lymphoma are predictive of outcome. J Nucl Med. 61. 40-45, 2020. DOI: 10.2967/jnumed.119.229450

  10. Provost C, Mammar H, Belly-Poinsignon A, Madar O, Champion L. Pharmacokinetic Analysis of [18F]FAZA Dynamic PET Imaging Acquisitions for Highlighting Sacrum Tumor Profiles. Clin Nucl Med. 45:e36-e38, 2020. DOI: 10.1097/RLU.0000000000002813

Publications 2018

  1. Boughdad S, Nioche C, Orlhac F, Jehl L, Champion L, Buvat I. Influence of age on radiomic features in 18F-FDG PET in normal breast tissue and in breast cancer tumors. Oncotarget. 9:30855-30868, 2018. DOI: 10.18632/oncotarget.25762

  2. Goutal S, Gerstenmayer M, Auvity S, Caillé F, Mériaux S, Buvat I, Larrat B, Tournier N. Physical blood-brain barrier disruption induced by focused ultrasound does not overcome the transporter-mediated efflux of erlotinib. J Control Release. 292:210-220, 2018.

  3. Nioche C, Orlhac F, Boughdad S, Reuzé S, Goya-Outi J, Robert C, Barakat C, Soussan M, Frouin F, Buvat I. LIFEx: a freeware for radiomic feature calculation in multimodality imaging to accelerate advances in the characterization of tumor heterogeneity. Cancer Res. 78:4786-4789, 2018. version PDF

  4. Reuzé S, Schernberg A, Orlhac F, Sun R, Dercle L, Deutsch E, Buvat I, Robert C. Radiomics in Nuclear Medicine applied to Radiation Therapy: methods, pitfalls and challenges. Int J Radiat Oncol Biol Phys. 102:1117-1142, 2018. version PDF. DOI: 10.1016/j.ijrobp.2018.05.022

  5. Auvity S, Caillé F, Marie S, Wimberley C, Bauer M, Langer O, Buvat I, Goutal S, Tournier N. P-glycoprotein (ABCB1) inhibits the influx and increases the efflux of 11C-metoclopramide across the blood-brain barrier: a PET study on non-human primates. J Nucl Med. 59:1609-1615, 2018.

  6. Goya-Outi J, Orlhac F, Calmon R, Alentorn A, Nioche C, Philippe C, Puget S, Boddaert N, Buvat I, Grill J, Frouin V, Frouin F. Computation of reliable textural indices from multimodal brain MRI: suggestions based on a study of patients with diffuse intrinsic pontine glioma. Phys Med Biol. 63:105003, 2018. version PDF

  7. Cottereau AS, Buvat I, Kanoun S, Versari A, Casasnovas O, Chauvie S, Clerc J, Gallamini A, Meignan M. Is there an optimal method for measuring baseline metabolic tumour volume in diffuse large B cell lymphoma? Eur J Nucl Med Mol Imaging. 45:1463-1464, 2018. version PDF

  8. Nguyen DL, Wimberley C, Truillet C, Jego B, Caillé F, Pottier G, Boisgard R, Buvat I, Bouilleret V. Longitudinal positron emission tomography imaging of glial cell activation in a mouse model of mesial temporal lobe epilepsy: Toward identification of optimal treatment windows. Epilepsia. 59:1234-1244, 2018. version PDF

  9. Orlhac F, Boughdad S, Philippe C, Stalla-Bourdillon H, Nioche C, Champion L, Soussan M, Frouin F, Frouin V, Buvat I. A post-reconstruction harmonization method for multicenter radiomic studies in PET. J Nucl Med. 59:1321–1328, 2018. version PDF

  10. Kucharczak F, Loquin K, Buvat I, Strauss O, Mariano-Goulart D. Interval-based reconstruction for uncertainty quantification in PET. Phys Med Biol. 63: 035014, 2018. version PDF

  11. Wimberley C, Lavisse S, Peyronneau MA, Brulon V, Leroy C, Remy P, Stankoff B, Buvat I, Bottlaender M. The impact of endothelial TSPO on the quantification of 18F-DPA714 in the healthy human. J Nucl Med. 59: 307-314, 2018. version PDF

  12. Schernberg A, Reuzé S, Orlhac F, Buvat I, Dercle L, Sun R, Limkin E, Escande A, Haie-Meder C, Deutsch E, Robert C. A score combining baseline neutrophilia and the SUVpeak of the primary tumor on FDG-PET predicts outcome in locally advanced cervical cancer. Eur J Nucl Med Mol Imaging. 45:187-195, 2018. version PDF

  13. Saba W, Goutal S, Auvity S, Kuhnast B, Coulon C, Kouyoumdjian V, Buvat I, Leroy C, Tournier N. Imaging the neuroimmune response to alcohol exposure in adolescent baboons: a TSPO PET study using 18F-DPA-714. Addict Biol. 23:1000-1009, 2018.

  14. Vandenberghe ME, Souedet N, Hérard AS, Ayral AM, Letronne F, Balbastre Y, Sadouni E, Hantraye P, Dhenain M, Frouin F, Lambert JC, Delzescaux T. Voxel-Based Statistical Analysis of 3D Immunostained Tissue Imaging. Front Neurosci. 12:754, 2018.

  15. Lazard DS, Bergeret-Cassagne H, Lefort M, Leenhardt L, Russ G, Frouin F, Trésallet C. Transcutaneous Laryngeal Ultrasonography for Laryngeal Immobility Diagnosis in Patients with Voice Disorders After Thyroid/Parathyroid Surgery. World J Surg. 42:2102-2108, 2018.

  16. Provost C, Prignon A, Rozenblum-Beddok L, Bruyer Q, Dumont S, Merabtene F, Nataf V, Bouteiller C, Talbot JN. Comparison and evaluation of two RGD peptides labelled with 68Ga or 18F for PET imaging of angiogenesis in animal models of human glioblastoma or lung carcinoma. Oncotarget. 9:19307-19316, 2018.

Publications 2019

  1. Buvat I, Orlhac F. The dark side of radiomics: on the paramount importance of publishing negative results. J Nucl Med. 60:1543-1544, 2019. DOI: 10.2967/jnumed.119.235325

  2. Dirand AS, Frouin F, Buvat I. A downsampling strategy to assess the predictive value of radiomic features. Sci Rep. 9:17869, 2019. version en ligne. DOI: 10.1038/s41598-019-54190-2

  3. Laurent C, Ricard L, Fain O, Buvat I, Adedjouma A, Soussan M, Mekinian A. PET/MRI in large-vessel vasculitis: clinical value for diagnosis and assessment of disease activity. Sci Rep. 9:12388, 2019. version en ligne. DOI: 10.1038/s41598-019-48709-w

  4. De Marzi L, Da Fonseca A, Moignier C, Patriarca A, Goudjil F, Mazal A, Buvat I, Hérault J. Experimental characterisation of a proton kernel model for pencil beam scanning techniques. Phys Med. 64:195-203, 2019. version PDF. DOI: 10.1016/j.ejmp.2019.07.013

  5. Veit-Haibach I, Buvat I, Herrmann K. AI and Radiomics in Nuclear Medicine and Hybrid Imaging: potential, challenges and clinical role. Eur J Nucl Med Mol Imaging. 46: 2627-2629, 2019. DOI: 10.1007/s00259-019-04395-4

  6. Orlhac F, Frouin F, Nioche C, Ayache N, Buvat I. Validation of a method to compensate multicenter effects affecting CT radiomic features. Radiology. 91:53-59, 2019. DOI: 10.1148/radiol.2019182023

  7. Goldfarb L, Duchemann B, Chouahnia K, Zelek L, Soussan M. Monitoring anti-PD-L1-based immunotherapy in non-small cell lung cancer with FDG PET: introduction of iPERCIST. EJNMMI Res.9:8, 2019. version en ligne 

  8. Prignon A, Provost C, Alshoukr F, Wendum D, Couvelard A, Barbet J, Forgez P, Talbot JN, Gruaz-Guyon A. Preclinical Evaluation of 68Ga-DOTA-NT-20.3: A Promising PET Imaging Probe To Discriminate Human Pancreatic Ductal Adenocarcinoma from Pancreatitis. Mol Pharm. 16:2776-2784, 2019.

  9. Provost C, Rozenblum-Beddok L, Nataf V, Merabtene F, Prignon A, Talbot JN. [68Ga]RGD Versus [18F]FDG PET Imaging in Monitoring Treatment Response of a Mouse Model of Human Glioblastoma Tumor with Bevacizumab and/or Temozolomide. Mol Imaging Biol. 21:297-305, 2019.

  10. Cassou-Mounat T, Champion L, Bozec L, Laurence V, Huchet V, Luporsi M, Jehanno N. Primary and Secondary Breast Angiosarcoma: FDG PET/CT Series. Clin Nucl Med. 44:e33-e35, 2019.

  11. Bando-Delaunay A, Luporsi M, Huchet V, Cassou-Mounat T, Jehanno N. A Case of Sarcoidosis After Lymphoma. Clin Nucl Med. 44:646-647, 2019.

  12. Jehanno N, Cassou-Mounat T, Mammar H, Luporsi M, Huchet V. 18F-Choline PET/CT Imaging for Intracranial Hemangiopericytoma Recurrence. Clin Nucl Med. 44:e305-e307, 2019.

  13. Cassou-Mounat T, Luporsi M, Huchet V, Jehanno N. Gallbladder Metastasis From Conjunctival Melanoma. Clin Nucl Med. 44:e107-e109, 2019.