Characterization of VOCAL fold motion and monItoring of Speech thErapy using dynamic translaryngeal ultrasound

Dynamic translaryngeal ultrasound (dTLUS), a non-invasive and inexpensive technique, has emerged in recent years as an alternative to nasofibroscopy, a minimally invasive method to assess vocal cord paralysis. 

The objective of VOCALISE is to propose a new approach allowing a better characterization of postoperative or radiation-induced dysphonia. It consists in associating to the dTLUS optimized acquisitions of the vibration of each vocal cord during phonation simultaneously with voice/speech recordings. 

Data acquired for the clinical trial VOCALE will be used to test our new software components for assessing vocal fold mobility.  The global approach will also be evaluated to monitor speech therapy in patients with recurrent nerve injury (clinical trial in the process of approval) and to qualify radiation-induced dysphonia in patients with Head and Neck cancers treated with radiotherapy.

For this project, four academic partners: LITO, LIB, LPP and Avicenne Hospital (Departments of Surgery and Nuclear Medicine) have joined forces with two industrial partners: Mindray Medical France and Apteryx. A collaboration with the Godinot Institute in Reims is underway.

People involved in the lab: Arnaud Beddok, Trung Kien Bui, Juliette Dindart, Frédérique Frouin, Agnès Rouxel. Alumini: Lydia Abdemeziem, Fahad Khalid 

Publications : hal-04623096v1

https://www.icvpb-2024.de/documents/8/Program_ICVPB2024.pdf pp 38-39 & pp 41-42

Project funded by ANR (ANR-22-CE19-0035)