Contribution of MRI radiomic analysis for the prediction of pathological Complete Response in breast cancer treated by neoadjuvant chemotherapy
The goal of the NeoTex project is to improve the early prediction of pathological complete response to neoadjuvant chemotherapy in patients with locally advanced or aggressive breast cancer and to propose new biomarkers of response. Features extracted from MRI scans performed at diagnosis and at mid-term are taken into account for the definition of predictive models, combining qualitative (BI-RADS criteria), quantitative (radiomic features), clinical and histopathological data.
An on-line model was developed to predict axillary residual disease after neoadjuvant chemotherapy.
Publications: DOI:10.26044/ecr2024/C-18261, DOI:10.1007/s00330-023-09797-5, DOI:10.1007/s00330-022-09113-7, DOI:10.1109/EMBC48229.2022.9871844, DOI:10.1007/s10334-020-00892-y
People involved in the laboratory: Caroline Malhaire (PI), Hervé Brisse, Frédérique Frouin, Fanny Orlhac, Paul Steinmetz. Alumni : Cédric Cordoba, Mathilde Droguet, Marie-Judith Saint-Martin