Publications 2025

  1. Amrane K, Cabarrou B, Le Meur C, Bourhis D, Pradier O, Misery L, Legoupil D, Etienne M, Fontaine GP, Salaun PY, Buvat I, Orlhac F, Abgral R. Prognostic Value of TMTV and Dmax calculated from 18F-fluorodeoxyglucose positron emission tomography images in metastatic cutaneous melanoma treated with immune checkpoint blockade. Eur J Nucl Med Mol Imaging, in press, 2025.

  2. Gesualdi F, Ermeneux L, Lansonneur P, Sitarz M, Loap P, Créhange G, Magliari A, De Marzi L. Comparison of protons and very high-energy electrons transmission pencil-beam-scanning for FLASH radiotherapy, Phys Imaging Radiat Oncol,36:100860, 2025. DOI: 10.1016/j.phro.2025.100860

  3. Iturri L, Riquelme-Perez M, Bonté PE, Potiron S, Goudot C, Juchaux M, Brisebard E, Gilbert C, Espenon J, Ortiz R, Patriarca A, De Marzi L, Amigorena S, Prezado Y. Evaluation of Proton Minibeam Radiotherapy on Antitumor Immune Responses in a Rat Model of Glioblastoma. Cancer Immunol Res, 13(11):1854-1872, 2025. DOI: 10.1158/2326-6066.CIR-24-0902

  4. Flacco A, Bayart E, Romagnani L, Cavallone M, De Marzi L, Fouillade C, Giaccaglia C, Heinrich S, Lamarre-Jouenne I, Monzac J, Parodi K, Patriarca A, Rösch T, Schreiber J, Tischendorf L. Laser driven FLASH radiobiology using a high dose and ultra high dose rate single pulse proton source. Sci Rep. 15(1):16511, 2025. DOI: 10.1038/s41598-025-01105-z

  5. Loap P, Vu-Bezin J, De Marzi L, Kirova Y. Impact of deep inspiration breath-hold and fractionation on immune system exposure in breast radiotherapy. Br J Radiol, 98(1173):1390-1393, 2025. DOI: 10.1093/bjr/tqaf113

  6. Prezado Y, Lamirault C, Jouglar E, Ahire V, Gilbert C, Espenon J, Bertho A, Iturri L, Pouzoulet F, de Marzi L, Patriarca A, Warfving N, Weber K, Juchaux M. Proton minibeam radiation therapy: A promising alternative for brain re-irradiations. Radiother Oncol, 209:110980, 2025. DOI: 10.1016/j.radonc.2025.110980

  7. Sokol O, Frederiksen AT, Sitarz M, Sørensen BS, Santina E, Smith C, Warmenhoven JW, Davídková M, Michaelidesová AJ, Danilová I, Zahradníček O, Leite AM, de Marzi L, Pouzoulet F, Olko P, Miszczyk J, Orzechowska B, Papalanis E, Hariri M, Spiegelberg D, Stenerlöw B, Dasu A, Bodenstein E, Beyreuther E, Pawelke J, Pfitzmann D, Kirkby K, Henthorn N, Durante M. In vitro measurement of proton RBE: A multi-centric comparison using a harmonized setup. Clin Transl Radiat Oncol, 53:100978, 2025. DOI: 10.1016/j.ctro.2025.100978

  8. Potiron S, Iturri L, Lamirault C, Dos Santos M, Corvino A, Fernandez-Rodriguez A, De Marzi L, Espenon J, Gilbert C, Juchaux M, Larcher T, Créhange G, Griffin R, Prezado Y. Dose Heterogeneity Reduces Radiation Oxygen Dependence in Both Tumor and Healthy Tissues: The Case of Proton Minibeam Radiation Therapy. Int J Radiat Oncol Biol Phys, 15;123(4):1132-1145, 2025. DOI: 10.1016/j.ijrobp.2025.06.3859

  9. Loap P, Goudjil F, de Marzi L, Cao K, Dendale R, Kirova Y. Proton therapy in young breast cancer patients with germline TP53 and ATM mutations: a case series. Strahlenther Onkol, 2025. DOI: 10.1007/s00066-025-02411-1.

  10. Auriac J, Nioche C, Hovhannisyan-Baghdasarian N, Loisel C, Seban RD, Jehanno N, Sundar LKS, Beyer T, Buvat I, Orlhac F. Comparison of organ volumes and standardized uptake values in [18F]FDG-PET/CT images using MOOSE and TotalSegmentator to segment CT images. Med Phys, 52(10):e70025, 2025. DOI: 10.1002/mp.70025

  11. Dierickx LO, Bettiol C, Huglo D, Marcelli F, Sibert L, Gouel P, Balamoutoff N, Ferretti L, Orlhac F, Huyghe E. Is 18F-Fluorodexyglucose testicular uptake using Positon Emission Tomography/Computed Tomography correlated with the results of a testicular sperm extraction procedure in the case of azoospermia (French prospective multicenter AZOPREDHISTOTEP study)? Eur J Nucl Med Mol Imaging, in press, 2025.

  12. Seban RD, Rebaud L, Djerroudi L, Vincent-Salomon A, Bidard FC, Champion L, Buvat I. Are [18F]FDG PET/CT imaging and cell blood count-derived biomarkers robust non-invasive surrogates for tumor-infiltrating lymphocytes in early-stage breast cancer? Ann Nucl Med, 39(12):1347-1358, 2025. DOI: 10.1007/s12149-025-02098-5

  13. Beddok A, Grogg K, Rozenblum L, Nioche C, Orlhac F, Calugaru V, Crehange G, Shih H, Marin T, Buvat I, El Fakhri G. Predicting Tumor Recurrence Site After Reirradiation in Head and Neck Cancer: A Retrospective External Validation of a Published [18F]-FDG PET Radiomic Signature. Radiol Med, 130(11):1854-1863, 2025. DOI: 10.1007/s11547-025-02072-1
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  15. Beddok A, Rozenblum L, Calugaru V, Feuvret L, Champion L, Ala Eddine C, Crehange G, El Fakhri G, Buvat I. Multimodal imaging to improve patient selection and optimize treatment planning and delivery for patients undergoing reirradiation: a scoping review. Curr Oncol Rep, 27(10):1155-1169, 2025. DOI: 10.1007/s11912-025-01708-9

  16. Marquis H, Erlandsson K, Buvat I. Addressing Partial Volume Effects in Clinical PET Quantification: Modern Correction Strategies and Challenges, PET Clinics, 20(4):407-422, 2025. DOI: 10.1016/j.cpet.2025.07.001

  17. Boellaard R, Rahmim A, Eertink CJ, Duhrsen U, Kurch L, Lugtenburg P, Wiegers S, Zwezerijnen GJC, Zijlstra JM, Heymans M, Buvat I. Summary report of the SNMMI AI Task Force Radiomics Challenge 2024. J Nucl Med, 66(8):1169-1175, 2025. DOI: 10.2967/jnumed.124.269425

  18. Czernin J, Anderson CJ, Badawi RD, Barthel H, Bengel FM, Beyer T, Buvat I, Calais J, Dorbala S, Drzezga AE, Herrmann K, Hope TA, Jadvar H, Mankoff DA, Schelbert HR, Weber WA. Funding Reductions Threaten the Future of Medical Innovation. J Nucl Med, 6(6):829, 2025. DOI: 10.2967/jnumed.125.270157.

  19. Buvat I, Dutta J, Jha AK, Siegel E, Yousefirizi F, Rahmim A, Bradshaw T. Should end-to-end deep learning replace handcrafted radiomics? Eur J Nucl Med Mol Imaging, 52(12):4360-4363, 2025. DOI: 10.1007/s00259-025-07314-y

  20. Boellaard R, Zwezerijnen GJC, Buvat I, Champion L, Hovhannisyan-Baghdasaria.n N, Orlhac F, Arens AIJ, Lobeek D , Celik F, Mitea C, Huijbregts JE, Tolboom N, de Keizer B, Valkema R, van Velden FHP, Dibbets-Schneider P, Wiegers SE, Lugtenburg PJ, Barrington SF, Zijlstra JM. Measuring total metabolic tumor volume from 18F-FDG PET – a reality check. J Nucl Med, 66(5):802-805, 2025. DOI: 10.2967/jnumed.124.269271

  21. Ronga MG, Gesualdi F, Bonfrate A, Patriarca A, Ferrand R, Crehange G,  Buvat I, De Marzi L. Comparison of secondary radiation dose contribution between pencil beam scanning and scattered delivery for proton and VHEE radiotherapy, Med Phys, 52(6):4775-4784, 2025. DOI: https://aapm.onlinelibrary.wiley.com/doi/10.1002/mp.17700

  22. Malhaire C, Umay O, Cockenpot V, Selhane F, Ramtohul T, Reyal F, Pierga JY, Romano E, Vincent-Salomon A, Kirova Y, Laas E, Brisse HJ, Frouin F. Predicting axillary residual disease after neoadjuvant therapy in breast cancer using baseline MRI and ultrasound. Eur Radiol, 35(8):4896-4909, 2025. DOI: 10.1007/s00330-025-11408-4

  23. Seban RD, Buvat I, Champion L, Bidard FC, Kieffer Y, Vincent-Salomon A, Peltier A, Mechta-Grigoriou F. Beyond FAP: ANTXR1 as a Novel Target for PET Imaging and Radio-Ligand Therapy in Immuno-Oncology? (Letter to the editor). Eur J Nucl Med Mol Imaging, 52(6):1948-1950, 2025. https://link.springer.com/article/10.1007/s00259-025-07126-0

  24. Lehrer EJ,  Khunsriraksakul C, Garrett S, Trifiletti DM, Sheehan JP, Guckenberger M, Louie AV, Siva S, Ost P, Goodman KA, Dawson LA, Tchelebi LT, Yang JT, Showalter TN, Park HS, Spratt DE, Kishan AU, Gupta GP, Shah C, Fanti S, Calais J, Wang M, Schmitz K, Liu D, Abraham JA, Dess RT, Buvat I, Solomon B, Zaorsky NG. Future directions in the evaluation and management of newly diagnosed metastatic cancer. Crit Rev Oncol Hematol, 104631, 2025. DOI: https://doi.org/10.1016/j.critrevonc.2025.104631

  25. Jouglar E, de Marzi L, Verrelle P, Créhange G, Ferrand R, Doz F, Prezado Y, Paoletti X. From pre-clinical studies to human treatment with proton-minibeam radiation therapy: adapted Idea, Development, Exploration, Assessment and Long-term evaluation (IDEAL) framework for innovation in radiotherapy. Clin Transl Radiat Oncol. 19;52:100932, 2025.  DOI: 10.1016/j.ctro.2025.100932.

  26. Lekadir K, Frangi AF, Porras AR, Glocker B, Cintas C, Langlotz CP, Weicken E, Asselbergs FW, Prior F, Collins GS, Kaissis G, Tsakou G, Buvat I, Kalpathy-Cramer J, Mongan J, Schnabel JA, Kushibar K, Riklund K, Marias K, Amugongo LM, Fromont LA, Maier-Hein L, Alberich LC, Martí-Bonmatí L, Cardoso MJ, Bobowicz M, Shabani M, Tsiknakis M, Zuluaga MA, Fritzsche MC, Camacho M, Linguraru MG, Wenzel M, De Bruijne M, Tolsgaard MG, Goisauf M, Abadía MC, Papanikolaou N, Lazrak N, Pujol O, Osuala R, Napel S, Joshi S, Klein S, Aussó S, Rogers WA, Puig-Bosch X, Salahuddin Z, Starmans MPA, and the FUTURE-AI Consortium. FUTURE-AI: International consensus guideline for trustworthy and deployable artificial intelligence in healthcare. BMJ British Medical Journal, 388, 2025. DOI: https://doi.org/10.1136/bmj-2024-081554.

  27. Captier N, Lerousseau M, Orlhac F, Hovhannisyan-Baghdasarian N, Luporsi M, Woff E, Lagha S, Salamoun Feghali P, Lonjou C, Beaulaton C, Salmon H, Walter T, Buvat I, Girard N, Barillot E. Integration of clinical, pathological, radiological, and transcriptomic data improves the prediction of first-line immunotherapy outcome in metastatic non-small cell lung cancer. Nature Comm, 16:614, 2025. DOI: https://doi.org/10.1038/s41467-025-55847-5

  28. Seban RD, Champion L, De Moura A, Lerebours F, Loirat D, Pierga JY, Djerroudi L, Genevee T, Huchet V, Jehanno N, Bidard FC, Buvat I. Pre-treatment [18F]FDG PET/CT biomarkers for the prediction of antibody-drug conjugates efficacy in metastatic breast cancer, Eur J Nucl Med Mol Imaging, 52(2):708-718, 2025. DOI: https://doi.org/0.1007/s00259-024-06929-x

  29. Prezado Y, Lamirault C, Larcher T, Gilbert C, Espenon J, Patriarca A, de Marzi L, Corvino A, Ortiz R, Juchaux M. On the significance of peak dose in normal tissue toxicity in spatially fractionated radiotherapy: The case of proton minibeam radiation therapy. Radiother Oncol. 205:110769, 2025. DOI: 10.1016/j.radonc.2025.110769

  30. Sitarz M, Ronga MG, Gesualdi F, Bonfrate A, Wahl N, De Marzi L. Implementation and validation of a very-high-energy electron model in the matRad treatment planning system. Med Phys, 52(1):518-529, 2025. DOI: 10.1002/mp.17392.

  31. Bonfrate A, Ronga MG, Patriarca A, Heinrich S, De Marzi L. Monte Carlo modeling of a commercial machine and experimental setup for Flash-Minibeam irradiations with electrons. Med Phys, 52(2):1224-1234, 2025. DOI: 10.1002/mp.17492

  32. Legdeur N, Badissi M, Venkatraghavan V, Woodworth DC, Orlhac F, Vidal JS, Barkhof F, Kawas CH, Visser PJ, Corrada MM, Muller M, Rhodius-Meester HFM. The temporal relation of physical function with cognition and the influence of brain health in the oldest-old: The UCI 90+ Study and EMIF-AD 90+ Study. Gerontology, 71(1):13-27, 2025. DOI: 10.1159/000542395